Adenovirus E1B shuttle vectors
US6764674B1 · kind B1 · utility
5Cited by
6References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 27, 1999 |
| Grant date | Jul 20, 2004 |
| Priority date | — |
| Expiry date | Dec 27, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/10343
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are replication competent, recombinant adenovirus vectors containing mutations in the E1B region which permit the easy deletion of a gene or genes therein, and optionally the substitution therefore of a heterologous gene that substantially exhibits the temporal expression pattern of the E1b region gene(s) deleted. Such vectors have applications for the treatment of disease, and preferably for the treatment of neoplastic disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.