Enantioselective bioreduction for the preparation of integrin receptor antagonist intermediates
US6764842B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Mar 27, 2002 |
| Grant date | Jul 20, 2004 |
| Priority date | — |
| Expiry date | Apr 24, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/182
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a novel enantioselective bioreduction using a yeast microorganism for the preparation of the chiral allylic alcohols of structural formula I (R is hydrogen or methyl) which are useful in the asymmetric synthesis of integrin &agr;v&bgr;3 receptor antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.