DNA sequence encoding a novel glucuronyl C5-epimerase
US6764844B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 18, 1999 |
| Grant date | Jul 20, 2004 |
| Priority date | — |
| Expiry date | Oct 18, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/90
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An isolated or recombinant DNA sequence coding for a mammalian, including human, glucuronyl C5-epimerase or a functional derivative thereof capable or converting D-glucuronyl acid (GlcA) to L-iduronic acid (IdoA); a recombinant expression vector comprising such DNA sequence; a host cell transformed with such recombinant expression vector; a process for manufacture of a glucuronyl C5-epimerase or functional derivative thereof capable of coverting GlcA to IdoA, comprising cultivation of a cell-line transformed with such recombinant expression vector; and a glucuronyl C5-epimerase or functional derivative thereof prepared by such process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.