Sol-gel encapsulation of lipid vesicles, lipid membranes and proteins
US6767483B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 21, 2001 |
| Grant date | Jul 27, 2004 |
| Priority date | — |
| Expiry date | Aug 21, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1273
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Inorganic-organic hybrid mixture sol-gel encapsulated lipid vesicles which are composed of silyl lipids or a mixture of silyl lipids and phospholipids are provided. The present invention also provides encapsulated Langmuir Blogget (LB) membranes and biological macromolecules. The sol-gel encapsulated lipid vesicles, LB membranes and proteins possess a higher stability than conventional vesicles. Inorganic-organic hybrid mixture sol-gels are provided as novel sol-gel materials possessing desirable mechanical and physicochemical properties. Also provided are methods of preparing encapsulated lipid vesicles, LB membranes and proteins. Methods of performing renal dialysis using compositions of the invention are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.