Recombinant Staphylococcus thioredoxin reductase and inhibitors thereof useful as antimicrobial agents
US6767536B1 · kind B1 · utility
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8Claims
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Key dates
| Filing date | Mar 2, 1999 |
| Grant date | Jul 27, 2004 |
| Priority date | — |
| Expiry date | Mar 2, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/0036
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Isolated and purified Staphylococcus thioredoxin reductases (TrxB) are provided. Polynucleotides encoding the TrxBs, vectors and host cells containing such polynucleotides are also provided. In addition, antibodies reactive with the TrxBs are provided, as are methods of isolating the TrxBs, as well as methods for producing recombinant TrxBs, using TrxBs for screening compounds for TrxB-modulating activity, and detecting Staphylococcus in a test sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.