Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137
US6767722B1 · kind B1 · utility
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38References
29Claims
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Key dates
| Filing date | Nov 28, 2000 |
| Grant date | Jul 27, 2004 |
| Priority date | — |
| Expiry date | Jan 18, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to muteins of human basic fibroblast growth factor with superagonist properties. Both protein and the respective encoding nucleic acid species are disclosed. The invention also embodies vectors and host cells for the propagation of said nucleic acid sequences and the production of said muteins. Also disclosed is a method for stimulating cell division.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.