Lipid matrix-drug conjugates particle for controlled release of active ingredient

US6770299B1 · kind B1 · utility

Assignee

• PHARMASOL GMBH · DE

Inventors

• Rainer Muller · Penzberg, DE
• Carsten Olbrich · Berlin, DE

Key dates

• Filing date: Jan 14, 2002
• Grant date: Aug 3, 2004
• Expiry date: Jan 14, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to particulate active ingredient vehicles which are in the solid aggregate state at room temperature (20° C.) and consist of a pure lipid-drug conjugate (LDC) or a mixture of several LDCs as particle matrix, the bond in the LDC being effected by covalent bonding, electrostatic interactions, dipole moments, dispersion forces, ion interactions, hydrogen bridges and/or hydrophobic interactions.