Lung surfactant compositions with dynamic swelling behavior

US6770619B2 · kind B2 · utility

Inventors

• Marcus Larsson · Bjärred, SE
• Kare Larsson · Bjärred, SE
• Per Wollmer · Enköping, SE
• Burkhard Lachmann · Rotterdam, NL
• Johannes Jacobus Haitsma · Maassluis, NL

Key dates

• Filing date: Aug 31, 2001
• Grant date: Aug 3, 2004
• Expiry date: Aug 31, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Lung surfactant compositions are provided which can form a swelling phase when dispersed in a medium containing electrolytes. Hereby, a more active spreading of the lung surfactant into the alveoli can be obtained after administration to the lungs. Further provided are a pharmaceutical composition and a pharmaceutical kit comprising a lung surfactant composition as well as to a method for the treatment, prevention and/or diagnosis of respiratory distress syndrome or other pulmonary diseases that are associated with a deficiency of a lung surfactant.