Patent · US Expired

Polyamino acid-catalyzed process for the enantioselective epoixdation of &agr;,&bgr;-unsaturated enones and &agr;,&bgr;-unsaturated sulfones

US6770766B2 · kind B2 · utility

1Cited by

3References

21Claims

0Family size

Assignee

Bayer Chemicals AG · DE

Inventors

Thomas Geller · Odenthal, DE
Christa Kruger · Hachenburg, DE
Hans-Christian Militzer · Odenthal, DE

Key dates

Filing date	Jul 24, 2002
Grant date	Aug 3, 2004
Priority date	—
Expiry date	Jul 24, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a novel process that makes it possible to epoxidize &agr;,&bgr;-unsaturated enones or &agr;,&bgr;-unsaturated sulfones with high conversions and enantiomeric excesses in the presence of a water-soluble base, an oxidant, a diastereomer- and enantiomer-enriched homo-polyamino acid as catalyst, water, an organic solvent that is immiscible or has only limited miscibility with water, and a specific phase-transfer catalyst as cocatalyst.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.