Fluidization of particles for encapsulation in oral dosage pharmaceutical products
US6772801B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 14, 2003 |
| Grant date | Aug 10, 2004 |
| Priority date | — |
| Expiry date | May 14, 2023 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB65B1/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Encapsulated oral dosage pharmaceutical products are produced utilizing a system including a hopper and a dosator, where the hopper receives particles having irregular geometries and sizes greater than about 100 &mgr;m for delivery to the dosator. A gaseous fluid is directed into the hopper to fluidize particles within the hopper so as to minimize or eliminate the formation of voids within the bed of particles disposed within the hopper. The fluidization of the particles within the hopper maintains a substantially continuous and uniform flow of particles from the hopper to the dosator, which results in the formation of encapsulated products with desirable weights and particle size distributions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.