Pharmaceutically active compound and methods of use
US6774263B1 · kind B1 · utility
1Cited by
11References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 9, 1998 |
| Grant date | Aug 10, 2004 |
| Priority date | — |
| Expiry date | Oct 9, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to racemic and optically active N-(2-chloro-5-methylthiophenyl)-N′-(3-methylsulfinylphenyl)-N′-methylguanidine, N-(2-chloro-5-methylsulfinylphenyl)-1-(7-trifluoromethyl- 1,2,3,4-tetrahydroquinolinyl)carboximidamide, and N-(3-methylsulfinylphenyl)-N-methyl-N′-(2-chloro-5-methoxyphenyl)guanidine and pharmaceutically acceptable salts thereof, and pharmaceutical compositions and therapeutic methods of treatment that comprise such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.