Encapsulated cells producing viral particles

US6776985B1 · kind B1 · utility

Assignees

• Bavarian Nordic A/S · DK
• GSF-Gesellschaft fur Umwelt und Gesundheit GmbH · DE

Inventors

• Robert Saller · Egglkofen, DE
• Walter Gunzburg · Schwanenstadt, AT
• Brian Salmons · Singapore, SG

Key dates

• Filing date: Dec 23, 1997
• Grant date: Aug 17, 2004
• Expiry date: Oct 5, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/13043
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to encapsulated cells producing viral particles, especially retroviral particles containing the genome of a retroviral vector carrying therapeutic genes, to methods for the preparation of such encapsulated cells, as well as to the use of such encapsulated cells for the delivery of genes, especially therapeutic genes, to target organs/cells.