Recombinant expression of S-layer proteins

US6777202B2 · kind B2 · utility

Assignees

• Werner Lubitz · AT
• NANO-S Biotechnologie GmbH · AT

Inventors

• Werner Lubitz · Klosterneuburg, AT
• Uwe Sleytr · Wien, AT
• Beatrix Kuen · Pressbaum, AT
• Michaela Truppe · Linz, AT
• Stefan Howorka · London, GB
• Stepanka Resch · Pressbaum, AT
• Gerhard Schroll · Pressbaum, AT
• Margit Sara · Gänserndorf, AT

Key dates

• Filing date: Dec 2, 1998
• Grant date: Aug 17, 2004
• Expiry date: Dec 2, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/16722
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns a process for the recombinant production of S-layer proteins in gram-negative host cells. Furthermore the nucleotide sequence of a new S-layer gene and processes for the production of modified S-layer proteins are disclosed.