Patent · US Expired

Method for producing 2′ -deoxyribonucleoside

US6777208B2 · kind B2 · utility

0Cited by
0References
6Claims
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Assignee

Inventors

Key dates

Filing dateOct 25, 2001
Grant dateAug 17, 2004
Priority date—
Expiry dateOct 25, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P19/40
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A 2′-deoxyribonucleoside is produced by culturing a microorganism, which is transformed with a gene encoding a ribonucleotide reductase and in which 2′-deoxyribonucleoside degradation activity is decreased or eliminated by disrupting a gene encoding a purine nucleoside phosphorylase on chromosomal DNA, in a medium in which the microorganism can grow to produce the 2′-deoxyribonucleoside.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.