Patent · US Expired

Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

US6777560B2 · kind B2 · utility

1Cited by
25References
27Claims
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Key dates

Filing dateAug 6, 2003
Grant dateAug 17, 2004
Priority date
Expiry dateAug 6, 2023

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P3/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.