2-alkyl-5-halogen-pent-4-ene carboxylic acids and their production
US6777574B1 · kind B1 · utility
6Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 29, 2002 |
| Grant date | Aug 17, 2004 |
| Priority date | — |
| Expiry date | Apr 30, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I in the form of their racemates or enantiomers, preferably compounds of formula Ia whereinR4 is C1-C6alkyl, Z is chlorine, bromine or iodine, and X is —OH, chloride, bromide or iodide, or X forms an ester group with the carbonyl substituent, as well as salts of carboxylic acids. The compounds are valuable intermediates for the propagation of &dgr;-amino-&ggr;-hydroxy-&ohgr;-aryl-alkanecarboxamides, which exhibit renin-inhibiting properties and could be used as antihypertensive agents in pharmaceutical preparations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.