Preparation of sterile stabilized nanodispersions
US6780324B2 · kind B2 · utility
32Cited by
7References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 18, 2002 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Sep 27, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The instant invention is directed toward a process for the production of a sterile, stabilized nanodispersion or loaded micelle comprising a polymer and a biologically active composition; particularly to nanodispersions produced by rehydration of a freeze-dried cake produced via the direct lyophilization of a stabilized solution comprising a polymer, such as an amphiphilic block copolymer or a small molecular weight surfactant, a biologically active agent, an optional additive, and a suitable solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.