Patent · US Expired

Positively charged membrane

US6780327B1 · kind B1 · utility

46Cited by
36References
80Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 12, 2001
Grant dateAug 24, 2004
Priority date
Expiry dateDec 12, 2021

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01D2325/36
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

The present invention provides a positively charged microporous membrane having a protein binding capacity about 25 mg/ml or greater comprising a hydrophilic porous substrate and a crosslinked coating that provides a fixed positive charge to the membrane. The present invention further provides a positively charged microporous membrane comprising a porous substrate and a crosslinked coating comprising pendant cationic groups. The membranes of the present invention find use in a variety of applications including ion-exchange chromatography, macromolecular transfer, as well as detection, filtration and purification of biomolecules such as proteins, nucleic acids, endotoxins, and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.