Adjuvant for a vaccine composition
US6780421B1 · kind B1 · utility
36Cited by
6References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1997 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Sep 9, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An amphipathic compound including a sterol-derived lipophilic grouping bound to a cationic grouping for use as an adjuvant in the delivery of a vaccine composition. In a particular embodiment, the lipophilic grouping is a cholesterol derivative and the cationic grouping is a quaternary ammonium or a protonatable amine. A vaccine composition including one or more antigens with at least one amphipathic compound having a sterol-derived lipophilic grouping bound to a cationic grouping, is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.