Analysis of alpha integrins for the diagnosis of diabetic nephropathy

US6780603B1 · kind B1 · utility

Assignee

• Regents of the University of Minnesota · US

Inventors

• Photini-Effie C. Tsilibary · Minneapolis, US
• Aristidis S. Charonis · Minneapolis, US
• Suman Setty · Minneapolis, US
• Michael Mauer · Ettlingen, DE

Key dates

• Filing date: May 2, 2001
• Grant date: Aug 24, 2004
• Expiry date: May 2, 2021

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Analysis of alterations in integrin subunit expression, particularly &agr;1 and/or &agr;2 integrin subunit expression from integrin producing cells as compared to normal controls as a diagnostic method to identify individuals who have or are predisposed to pathologies associated with altered matrix deposition, such as diabetic renal nephropathy.