Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood
US6780850B1 · kind B1 · utility
9Cited by
2References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2000 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Jun 22, 2020 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is a complex of a polynucleotide having a property of specifically binding to a target protein together with a protein that stabilizes the polynucleotide from degradation and from clearance from the circulation in vivo. Methods for diagnostic imaging and therapeutic uses of the complex are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.