Pyrimidine derivatives
US6780869B1 · kind B1 · utility
20Cited by
1References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2002 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Aug 21, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides the compounds of formula (I) and pharmaceutically acceptable derivatives thereof, in which:R1 and R2 are independently selected from H, C1-6 alkyl, C2-6alkenyl, C3-6alkynyl, C3-10cycloalkylC0-6alkyl or C4-12bridged cycloalkane; and R3 is C1-6alkyl or NH2.Compounds of formula (I) are potent and selective inhibitors of COX-2 and are of use in the treatment of pain, fever, inflammation and a variety of conditions and diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.