Monocyclic compounds with four bifunctional residues having NK-2 antagonist action
US6780968B1 · kind B1 · utility
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13Claims
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Key dates
| Filing date | Jul 12, 2000 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Jul 12, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are monocyclic compounds containing four bifunctional residues linked together via peptide or pseudopeptide bonds of the general formula (I): having tachykinin receptor antagonist activity. In particular, compounds of formula I are shown to be neurokinin-2 (NK-2) antagonists useful in the treatment or prevention of disorders of the central nervous system, inflammatory diseases, asthma, or pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.