Charge tags and the separation of nucleic acid molecules
US6780982B2 · kind B2 · utility
69Cited by
31References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 6, 2001 |
| Grant date | Aug 24, 2004 |
| Priority date | — |
| Expiry date | Feb 6, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/683
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel phosphoramidites, including positive and neutrally charged compounds. The present invention also provides charge tags for attachment to materials including solid supports and nucleic acids, wherein the charge tags increase or decrease the net charge of the material. The present invention further provides methods for separating and characterizing molecules based on the charge differentials between modified and unmodified materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.