Method for producing a polynucleotide library in vitro by mismatch repair of heteroduplexes
US6783941B2 · kind B2 · utility
8Cited by
2References
17Claims
0Family size
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Key dates
| Filing date | Dec 5, 2001 |
| Grant date | Aug 31, 2004 |
| Priority date | — |
| Expiry date | Jun 27, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1027
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for making polynucleotide libraries that comprise new recombined polynucleotides by using mismatch repair enzymes or proteins to shuffle at least two variants of the same polynucleotide or at least two homologous polynucleotides through a Recombinatorial Chain Reaction, RCR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.