Patent · US Expired

Piperazine-containing compounds useful in the treatment of pain

US6784181B2 · kind B2 · utility

10Cited by
5References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 21, 2002
Grant dateAug 31, 2004
Priority date
Expiry dateDec 13, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D409/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to a compound of general formula (I), wherein R1 is selected from phenyl, pyridinyl, thiophenyl, furanyl, imidazolyl; each phenyl ring and heteroaromatic ring optionally and independently being further substituted by 1, 2 or 3 substituents selected from straight and branched C1-C6 alkyl, NO2, CF3, C1-C6 alkoxy, chloro, fluoro, bromo, and iodo, as well as their pharmaceutically acceptable salts. The invention includes pharmaceutical compositions comprising these compounds and the use of the compounds in therapy, in particular in the management of pain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.