Modifying tissue surfaces by liquid crystal formation
US6784282B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Jul 2, 2002 |
| Grant date | Aug 31, 2004 |
| Priority date | — |
| Expiry date | Oct 2, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2400/18
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method for modifying the surface properties of tissue in vivo is described. The method comprises forming a liquid crystalline matrix on the tissue surface wherein the matrix comprises a tissue surface component. In one embodiment there is provided a method for improving the bonding of surgical glues and cements to cartilage and other synovial fluid wetted tissue surfaces. Such surfaces are contacted with a composition comprising a poly(hydroxy substituted amino acid) to form a liquid crystalline matrix on the tissue surface. The matrix is readily removed to provide a tissue surface that exhibits improved bonding with surgical glues.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.