Plasma-derived fibrin-based matrices and tissue

US6787357B2 · kind B2 · utility

Assignee

• Virginia Commonwealth University · US

Inventors

• Gary Bowlin · Mechanicsville, US
• Gary Wnek · Cleveland, US
• David Simpson · Mechanicsville, US
• Philippe Lam · Richmond, US
• Marcus Carr · Holland, US
• Helen Fillmore · Richmond, US

Key dates

• Filing date: Oct 5, 2001
• Grant date: Sep 7, 2004
• Expiry date: Oct 5, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/56
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is directed to use of fibrin as an extracellular matrix and, together with cells, its use in forming engineered tissue. The engineered tissue can include the synthetic manufacture of specific organs or “organ-like” tissue. A preferred embodiment is a plasma-derived fibrin matrix containing cells.