Tumor specific human monoclonal antibodies and methods of use
US6787638B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 1998 |
| Grant date | Sep 7, 2004 |
| Priority date | — |
| Expiry date | Dec 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/565
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides tumor-specific human monoclonal antibodies and functional fragments. Also provided are nucleic acids encoding tumor-specific human monoclonal antibodies and functional fragments. A method for reducing neoplastic cell proliferation is also provided. The method consists of administering an effective amount of a tumor-specific human monoclonal antibody or functional fragment. Also provided is a method of detecting a neoplastic cell in a sample. The method consists of contacting a cell with a tumor-specific monoclonal antibody or functional fragment and detecting the specific binding of the human monoclonal antibody or functional fragment to the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.