Mobile phase dilution scheme for enhanced chromatography
US6790361B2 · kind B2 · utility
20Cited by
8References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 2003 |
| Grant date | Sep 14, 2004 |
| Priority date | — |
| Expiry date | Apr 14, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/347
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequently diluted with a weak mobile phase. The resulting sample-containing weak mobile phase is passed through a chromatography column for retention and separation of the components of the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.