Cell delivery system comprising a fibrous matrix and cells

US6790455B2 · kind B2 · utility

Assignee

• The Research Foundation at State University of New York · US

Inventors

• Benjamin Chu · Setauket, US
• Benjamin S. Hsiao · Setauket, US
• Michael Hadjiargyrou · Coram, US
• Dufei Fang · Corning, US
• Xinhua Zong · San Jose, US
• Kwangsok Kim · Setauket, US

Key dates

• Filing date: Sep 14, 2001
• Grant date: Sep 14, 2004
• Expiry date: Sep 14, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/40
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable fibrous matrix physically associated with viable cells to contain and release the cells at a controlled rate. The biodegradable and/or bioabsorbable matrix can be formed by electrospinning fibers of biodegradable and/or bioabsorbable fiberizable material. The methods include methods for storing viable cells and for delivering viable cells to a mammal using the cell storage and delivery system.