Patent · US Expired

Methods for treating diabetes via administration of controlled release metformin

US6790459B1 · kind B1 · utility

56Cited by
58References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 3, 2000
Grant dateSep 14, 2004
Priority date
Expiry dateMar 17, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/155
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method for treating patients having non-insulin-dependent diabetes mellitus (NIDDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as metformin, on a once-a-day basis. The dosage form provides a mean time to maximum plasma concentration (Tmax) of the drug which occurs at a 5.5 to 7.5 hours after oral administration on a once-a-day basis to human patients. Preferably, the dose of drug is administered at dinnertime to a patient in the fed state.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.