Megsin promoter
US6790617B1 · kind B1 · utility
Assignees
Inventor
Key dates
| Filing date | Oct 16, 2001 |
| Grant date | Sep 14, 2004 |
| Priority date | — |
| Expiry date | Oct 16, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Genomic DNA region including the about 1.5 kb upstream region of MEGSIN gene was isolated and its nucleotide sequence was determined. In the genomic DNA region, two regulatory sequences that regulate the transcription positively were identified. Furthermore, nucleotide substitutions were introduced in the promoter regions located at the 3′ sites of the two regulatory sequences by site specific mutagenesis, and the nucleotide sequences that play important roles in the promoter activity were successfully identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.