DNA encoding galanin GALR2 receptors

US6790656B1 · kind B1 · utility

Assignee

• Synaptic Pharmaceutical Corporation · US

Inventors

• Kelli E. Smith · Wayne, US
• Christophe P. G. Gerald · Ridgewood, US
• Richard L. Weinshank · Teaneck, US
• David L. Linemeyer · Guilford, US
• Theresa Branchek · Teaneck, US
• Carlos Forray · Paramus, US

Key dates

• Filing date: Jun 4, 1998
• Grant date: Sep 14, 2004
• Expiry date: Jun 4, 2018

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides isolated nucleic acids encoding mammalian galanin receptors, isolated galanin receptor proteins, vectors comprising isolated nucleic acid encoding a mammalian galanin receptor, cells comprising such vectors, antibodies directed to a mammalian galanin receptor, nucleic acid probes useful for detecting nucleic acid encoding a mammalian galanin receptor, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding a mammalian galanin receptor, nonhuman transgenic animals which express DNA encoding a normal or a mutant mammalian galanin receptor, as well as methods of determining binding of compounds to mammalian galanin receptors.