System for detecting bacteria in blood, blood products, and fluids of tissues
US6790661B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 14, 2000 |
| Grant date | Sep 14, 2004 |
| Priority date | — |
| Expiry date | Jul 14, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56911
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides methods for screening for the presence of a clinically relevant amount of bacteria in donor blood or a blood product from a donor mammal, particularly blood or a blood product that will be transferred from the donor mammal to a recipient mammal. The method comprises contacting a sample of the donor blood or a blood product with a set of binding agents that comprises binding agents that specifically bind to Gram-negative bacterial antigen and/or binding agents that specifically bind to Gram-positive bacterial antigen, and determining binding of the set of binding agents to the sample, wherein binding indicates the presence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product and no binding indicates the absence of a clinically relevant amount of Gram-positive bacteria and/or Gram-negative bacteria in the donor blood or blood product.The invention further provides methods and kits for screening for the presence of a clinically relevant amount of Gram-positive bacteria, Gram-negative bacteria, or both Gram-positive and Gram-negative bacteria in a donor tissue by screening the fluid in which t…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.