Quinoline, isoquinoline and phthalazine derivatives as antagonists of the gonadotropin-releasing hormone

US6790858B2 · kind B2 · utility

Assignee

• Zentaris GmbH · DE

Inventors

• Peter Strehlke · Berlin, DE
• Peter Droescher · Weimar, DE
• Ulrich Buehmann · Berlin, DE
• Norbert Schmees · Berlin, DE
• Peter Muhn · Berlin, DE
• Holger Hess-Stumpp · Berlin, DE
• Roland Kühne · Berlin, DE
• Eckhard Guenther · Maintal, DE
• Emmanuel Polymeropoulos · Frankfurt, DE
• Antonius Ter Laak · Berlin, DE

Key dates

• Filing date: Feb 21, 2002
• Grant date: Sep 14, 2004
• Expiry date: May 17, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to a compound of formula (I): where R1-R6, W, X, and Y are defined herein, a composition includung the compound of formula (I), and a method for, e.g., male birth control, including administering an effective amount of a compound of formula (I) to a patient in need thereof.