Ruthenium complexes and process for preparing alcoholic compounds using these
US6790973B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 2002 |
| Grant date | Sep 14, 2004 |
| Priority date | — |
| Expiry date | Jan 17, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F15/0053
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides novel ruthenium complexes having an optically active diphosphine compound, which has asymmetry on carbon and is easy to synthesize, as the ligand and a process for preparing optically active alcoholic compounds using said complexes as the catalysts, wherein said process is the process for preparing optically active alcoholic compounds, which are excellent in terms of reactivity, enatioselectivity and the like in an asymmetric hydrogenation of carbonyl compounds compared with conventional ruthenium complex catalysts having an optically active diphosphine compound having the axial chirality or the asymmetry on carbon as the ligand.In a preferred embodiment, the invention provides an optically active ruthenium complex represented by the general formula (1) wherein X and Y, which can be identical to or different from each other, represent a hydrogen atom or an anion group, R1 and R2, which can be identical to or different from each other, represent a chain or cyclic hydrocarbon group of carbon number 1 to 20, which can be substituted, R3 and R4, which can be identical to or different from each other, represent a hydrogen atom or a hydrocarbon group of carbon numb…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.