Iterative optimization in the design of binding proteins
US6794136B1 · kind B1 · utility
223Cited by
43References
19Claims
0Family size
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Key dates
| Filing date | Nov 20, 2000 |
| Grant date | Sep 21, 2004 |
| Priority date | — |
| Expiry date | May 2, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/102
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed herein are design methods for optimizing the specificity of a binding protein. The methods comprise iterative cycles of rational design, site selection, redesign and site selection of the redesigned molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.