Nucleic acid fragment and vector comprising a halogenase, and a process for halogenating chemical compounds

US6794170B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Stefan Pelzer · Gütersloh, DE
• Petra Huber · Munich, DE
• Roderich Suessmuth · Berlin, DE
• Juergen Recktenwald · Poltringen, DE
• Dorothee Heckmann · Schwalbach am Taunus, DE
• Wolfgang Wohlleben · Bielefeld, DE

Key dates

• Filing date: Apr 5, 2002
• Grant date: Sep 21, 2004
• Expiry date: Apr 5, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/14
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a process halogenation, which comprises halogenating a chemical compound in the presence of a halogenase, where the halogenase is(a) encoded by the sequence specified in SEQ ID NO: 1 or a sequence derived therefrom on the basis of the degeneracy of the genetic code, or is(b) encoded by a nucleic acid sequence which codes for a functional fragment of (a) or(c) by a sequence which hybridizes with (a) or (b) under standard conditions, or is(d) encoded by a sequence which has more than 30% identity or more than 60% similarity with the sequence specified under (a).