Patent · US Expired

Target

US6794192B2 · kind B2 · utility

29Cited by
4References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 28, 2001
Grant dateSep 21, 2004
Priority date
Expiry dateJun 25, 2022

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/105831
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to an isolated target sequence. The target sequence is a splice variant of PDE5 called a PDE5a1, a component of which is presented as SEQ ID No 1. The identified target sequence of the present invention may be used to as a target to identify agents (such as modulators) useful in the prevention and/or treatment of a disease associated with scarring and/or fibrosis or to selectively identify smooth muscle cells and myofibroblasts and myoepithelial cells in samples of normal and diseased tissue from individuals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.