Patent · US Expired

Antithrombin H-helix mutants

US6794493B2 · kind B2 · utility

2Cited by
0References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 6, 2001
Grant dateSep 21, 2004
Priority date—
Expiry dateAug 15, 2022

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/57
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Mutant antithrombin modified to carry a more positive charge in the H-helix is provided. The modified antithrombin modulates the activities of thrombin, and extends the bioavailability of factor VIII.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.