Process for the preparation of fluorosteroids
US6794503B2 · kind B2 · utility
2Cited by
10References
5Claims
0Family size
Assignee
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Key dates
| Filing date | May 16, 2001 |
| Grant date | Sep 21, 2004 |
| Priority date | — |
| Expiry date | May 16, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J71/0015
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein is a process for the preparation of 6&agr;-fluorosteroids of formula (I), in which R is chosen from H, OH and an alkyl group with from 1 to 4 carbon atoms and R′ is a carboxyalkyl group with from 1 to 4 carbon atoms in the alkyl chain, comprising the selective fluorination at the 6&agr;-position by treatment of the compound of formula (III), wherein R and R′ are as defined above, with an electrophilic fluorinating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.