Light modulated microarray reader and methods relating thereto
US6794658B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2002 |
| Grant date | Sep 21, 2004 |
| Priority date | — |
| Expiry date | Jul 13, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B27/021
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Microarray readers and methods that compensate for target spots that are too dim or too bright for the microarray reader to accurately measure. The readers adjust the amount of light directed at or received from specific non-acceptable target spots, such that dim spots receive more excitation light and overly bright spots receive less. This increases or decreases, respectively, their measured brightness, which in turn effectively increases the range over which a microarray reader can accurately measure the spots, and can also improve the signal-to-noise ratio and other aspects of the measurements.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.