Manganese superoxide dismutase regulatory elements and uses thereof
US6800458B1 · kind B1 · utility
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23Claims
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Key dates
| Filing date | Aug 28, 2001 |
| Grant date | Oct 5, 2004 |
| Priority date | — |
| Expiry date | Aug 28, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel transcriptional regulatory element which was isolated from the MnSOD gene and which exhibits promoter-enhancer activity is disclosed. The promoter-enhancer activity of the element is further modulated by inflammatory mediators to regulate transcription. Methods of using the promoter-enhancer element to regulate gene expression, and therapeutic uses involving the promoter-enhancer element are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.