Patent · US Expired

Modified factor VIII cDNA

US6800461B2 · kind B2 · utility

9Cited by

3References

4Claims

0Family size

Assignee

Aventis Behring GmbH · DE

Inventors

Claude Negrier · Irigny, FR
Jean-Luc Plantier · Val-de-Reuil, FR

Key dates

Filing date	Jun 15, 2001
Grant date	Oct 5, 2004
Priority date	—
Expiry date	Jun 15, 2021

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P7/04
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A modified Factor VIII cDNA is described in which the B-domain of the wild-type Factor VIII cDNA has been deleted and a truncated Factor IX intron 1 has been inserted in one or more locatons of the Factor VIII cDNA. Such modified Factor VIII cDNA may be used for a higher yield production of Factor VIII in vitro as well as in a transfervector for gene therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.