Stereoselective reduction of substituted acetophenone
US6800477B2 · kind B2 · utility
111Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2002 |
| Grant date | Oct 5, 2004 |
| Priority date | — |
| Expiry date | Jul 5, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/938
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to novel stereoselective processes for the preparation of (S)-1-arylethanols by the reduction of the corresponding keto group containing compounds by microorganisms. (S)-1-arylethanols are useful as intermediates in the synthesis of compounds that are inhibitors of &ggr;-secretase useful in the treatment of Alzheimer's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.