Antidepressant indolealkyl derivatives of heterocycle-fused benzodioxan methylamines

US6800637B2 · kind B2 · utility

Assignee

• Wyeth, LLC · US

Inventors

• Gary P. Stack · Ambler, US
• Michael Byron Webb · Douglassville, US
• Deborah Evrard · Hamilton Square, US
• Dahul Zhou · East Brunswick Township, US

Key dates

• Filing date: Sep 10, 2003
• Grant date: Oct 5, 2004
• Expiry date: Sep 10, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula: are useful for the treatment of depression (including but not limited to major depressive disorder, childhood depression and dysthymia), anxiety, panic disorder, post-traumatic stress disorder, premenstrual dysphoric disorder (also known as pre-menstrual syndrome), attention deficit disorder (with and without hyperactivity), obsessive compulsive disorder, social anxiety disorder, generalized anxiety disorder, obesity, eating disorders such as anorexia nervosa, bulimia nervosa, vasomotor flushing, cocaine and alcohol addiction, sexual dysfunction and related illnesses.