Crystal structure of cPLA2 and methods of identifying agonists and antagonists using same
US6801860B1 · kind B1 · utility
35Cited by
10References
7Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 15, 1999 |
| Grant date | Oct 5, 2004 |
| Priority date | — |
| Expiry date | Feb 15, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides for crystalline cPLA2. The crystal structure of cPLA2 has also been solved using such material. Models based upon such crystal structure are also provided. Methods of identifying inhibitors of cPLA2 activity and membrane binding using such models are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.