Patent · US Expired

Method for making a biochip and biochip

US6803228B1 · kind B1 · utility

5Cited by
8References
29Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 14, 2001
Grant dateOct 12, 2004
Priority date
Expiry dateJun 14, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC40B60/14
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention relates to a method to produce a biochip and to a biochip, said biochip being composed particularly of biological probes grafted onto a conductive polymer.The method according to the invention comprises the following steps:a) structuring of a substrate so as to obtain on said substrate microtroughs comprising in their base a layer of a material capable of initiating and promoting the adhesion onto said layer of a film of a pyrrole and functionalised pyrrole copolymer by electropolymerisation,b) collective electropolymerisation, so as to form an electropolymerised film of a pyrrole and functionalised pyrrole copolymer on the base of said microtroughs,c) direct or indirect fixation of functionalised oligonucleotides by microdeposition or a liquid jet printing technique.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.