Patent · US Expired

Spiro compounds

US6803372B2 · kind B2 · utility

10Cited by
1References
41Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 8, 2002
Grant dateOct 12, 2004
Priority date
Expiry dateMay 14, 2022

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds of the general formula (I): wherein Ar1 represents optionally substituted aryl or heteroaryl;n represents 0 or 1;T, U, V, and W each independently represent nitrogen atom or optionally substituted methine group, where at least two of them represent the said methine group;X represents methine or hydroxy substituted methine;Y represents an optionally substituted imino or oxygen atom are described and claimed. These novel spiro compounds are useful as neuropeptide Y receptor antagonists and as agents for the treatment of various kinds of cardiovascular disorders, central nervous system disorders, metabolic diseases and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.